Everything about Trimethylamine totally explained
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Trimethylamine, also known as
NMe3,
N(CH3)3, and
TMA, is a colorless,
hygroscopic, and flammable simple
amine with a typical fishy
odor in low
concentrations and an
ammonia-like odor in higher concentrations. Trimethylamine has a boiling point of 2.9 °C and is a gas at room temperature. Trimethylamine usually comes in pressurized
gas cylinders or as a 40%
solution in
water. Trimethylamine is a
nitrogenous base and its positively
charged cation is called
trimethylammonium cation. A common
salt of trimethylamine is
trimethylammonium chloride, a hygroscopic colorless solid.
Trimethylamine is a product of decomposition of plants and animals. It is the substance mainly responsible for the fishy odor often associated with fouling
fish,
bacterial
vagina infections, and
bad breath. It is also associated with taking large doses of
choline and
carnitine.
Applications
Trimethylamine is used in the
chemical synthesis of
choline,
tetramethylammonium hydroxide,
plant growth regulators, strongly basic
anion exchange resins, and
dye leveling agents. Its fish-like odor has proven useful in applications such as the creation of gas sensors to test for fish freshness.
Trimethylaminuria
Trimethylaminuria is a
genetic disorder in which the body is unable to
metabolize trimethylamine from food sources. Patients develop a characteristic fish odour of their
sweat,
urine, and
breath after the consumption of
choline-rich foods. Trimethylaminuria is an
autosomal recessive disorder involving a trimethylamine oxidase deficiency. A trimethylaminuria-like condition has also been observed in a certain breed of
Rhode Island Red
chicken that produces eggs with a fishy smell, especially after eating food containing a high proportion of
rapeseed.
Further Information
Get more info on 'Trimethylamine'.
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